Fathman Lab Alumni
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Yul Huh
Position: Graduate Student Researcher (M.S., Biological Sciences)
Education:
Undergraduate: Stanford University, B.S., Biological Sciences
Project: Characterization of novel anergy genes and their functionality in T cell activation and tumorigenesis.
Email:
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Deqiao Sheng, PhD
Position: Postdoctoral fellow
Education:
Graduate: Chinese Academy of Medical Science & Peking Union Medical College, Ph.D. Molecular Biology
Undergraduate: Xiamen University, B.S. Biology
Project: RoadMap of NOD T1D
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Emilie Vinolo, PhD
Position: Postdoctoral Fellow
Education:
Graduate: Ph.D. in biochemistry from Universite Pierre et Marie Curie/Institut Pasteur, Paris (France)
Undergraduate: French engineering school E.S.P.C.I., Chemistry major
Project: From my PhD dissertation work on the NF-ΚB essential modulator (NEMO) protein, I became interested in exploring the interface between ubiquitination and signaling in the immune system. As a result, I joined the Fathman lab to focus on two projects. First, several bodies of evidence suggest a possible role for lymphocyte activation gene 3 (LAG-3) in the negative regulation of T cell activation and the induction and/or maintenance of tolerance. I am presently trying to identify proteins that interact with LAG-3 cytoplasmic domain in order to gain further insight into LAG-3 intracellular signaling and its regulation of T cell function. Second, I am utilizing a structure-function approach to refine the model in which expression of the E3 ligase GRAIL is regulated by two deubiquitinating enzymes, Otubain 1 and USP8 (see Soares L. et al. Nat. Immunol. 2004).
Email:
Home Page: http://www.linkedin.com/in/evinoloprofile
